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SUMMARY:Naturally occurring micro reactors: phase separation as a regulate
 d strategy for compartmentalisation in cells. - Dr. Andrew Baldwin\, Oxfor
 d University
DTSTART:20151021T093000Z
DTEND:20151021T103000Z
UID:TALK61958@talks.cam.ac.uk
CONTACT:Jerome Charmet
DESCRIPTION:Polymer theory predicts weakly interacting disordered proteins
  should phase separate. I'll discuss some recent work where we demonstrate
  this phenomena with proteins\, and show that this mechanism is used for o
 rganelle creation and cell compartmentalization in Eukaryotic cells. The i
 nterior of these bodies\, which form reversibly and can be regulated with 
 post translational modifications\, amount to a solvent environment that is
  quite distinct from bulk water. Cells are effectively using the interior 
 of these bodies as an alternative solvent to bulk water\, much as an organ
 ic chemist would.
LOCATION:Department of Chemistry\, Cambridge\, Unilever lecture theater
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