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SUMMARY:'Altruistic suicide' as a bacterial defense mechanism against vira
 l infection - Bihe Chen
DTSTART:20151117T203000Z
DTEND:20151117T210000Z
UID:TALK62131@talks.cam.ac.uk
CONTACT:Paulina Rowicka
DESCRIPTION:Bacteriophages are viruses that infect bacteria and are consid
 ered one of the most abundant entities in the biosphere. Due to their effi
 ciency in infecting and killing bacteria\, bacteriophages are exploited fo
 r “phage therapy”\, i.e. using bacteriophages to control bacterial inf
 ection. In recent years bacteriophage research has come under the spotligh
 t due to growing antibiotic resistance and the need for alternative ways o
 f managing bacterial infection. However many obstacles still exist in phag
 e therapy research\, especially bacterial resistance to phage infection. I
 n this talk the audience will be given a brief introduction to bacteriopha
 ge biology and phage therapy\, followed by in-depth description of how som
 e bacteria could defend themselves against phage infection using Type III 
 toxin-antitoxin\, causing abortive infection\, a.k.a. “altruistic suicid
 e”.
LOCATION:Senior Parlour\, Gonville and Caius College
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