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SUMMARY:The Cancer Cell Map Initiative - Trey Ideker\, UC San Diego School
  of Medicine\, La Jolla\, CA
DTSTART:20161117T130000Z
DTEND:20161117T140000Z
UID:TALK62362@talks.cam.ac.uk
CONTACT:Kate Davenport
DESCRIPTION:One of the most striking outcomes of the cancer genome project
 s is that tumors of similar types and clinical responses can have patterns
  of mutations that are strikingly different. Despite these differences\, i
 t is becoming very clear that tumor alterations hijack the same hallmark m
 olecular pathways and networks. Thus\, a complete vision for cancer precis
 ion medicine requires not only genome sequencing\, but interpretation of t
 hese genomes against a comprehensive map of cancer molecular networks. We 
 have recently started The Cancer Cell Map Initiative (CCMI)\, aimed at sys
 tematically detailing the physical and genetic interactions among cancer g
 enes and how these connections differ between diseased and healthy states.
  I will describe recent progress in technology and thinking that supports 
 the creation of such a cancer cell map across a range of tissue types\, as
  well as how such a resource can be used to match patient genomes with pro
 gnostic and predictive outcomes. 
LOCATION:CRUK CI Lecture Theatre
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