BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Talks.cam//talks.cam.ac.uk// X-WR-CALNAME:Talks.cam BEGIN:VEVENT SUMMARY:Symmetry Matters in Gynoecium Development - Lars Ostergaard\, Head of Crop Genetics\, JIC DTSTART:20160218T160000Z DTEND:20160218T170000Z UID:TALK63120@talks.cam.ac.uk CONTACT:38889 DESCRIPTION:Interactions among key regulators of Arabidopsis gynoecium dev elopment have revealed a network of transcription factor activities requir ed for dividing this organ into discrete domains. Regulation of auxin dyna mics is emerging as an immediate downstream output from these activities. We aim to understand the spatiotemporal information that is defined throug h interactions between a set of transcription factors and auxin during the gynoecium patterning process. At the gynoecium apex\, our data suggest th at auxin is recruited to promote an unusual symmetry transition. We hypoth esise that this is required to eliminate a default state of bilateral symm etry engrained in the gynoecium from its origin as two fused leaves.\n\nAu xin signaling occurs through binding of the auxin molecule to a TIR1/AFB F -box protein allowing interaction with Aux/IAA transcriptional repressor p roteins. These are subsequently degraded via the 26S proteasome leading to de-repression of auxin response factors (ARFs). How auxin is able to elic it such a diverse range of developmental responses through a single signal ling module remains largely unclear. We have identified an alternate auxin -signalling mechanism comprised of a co-receptor complex involving the tra nscription factors ETTIN and INDEHISCENT directly binding the auxin molecu le. This auxin co-receptor is important for coordinated development of tis sues in the Arabidopsis female reproductive organ – the gynoecium. Disru pting the auxin-binding capacity of this co-receptor compromises developme nt of the apical tissues of the gynoecium severely affecting plant fertili ty.\n LOCATION:Department of Plant Sciences\, Large Lecture Theatre END:VEVENT END:VCALENDAR