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SUMMARY:Pleasures of the brain: Investigating anhedonia with whole-brain c
 omputational connectomics  - Professor Morten L. Kringelbach Department of
  Psychiatry\, Warneford Hospital\, University of Oxford\, United Kingdom D
 epartment of Clinical Medicine - Center for Music In the Brain\, Aarhus Un
 iversity\, Denmark 
DTSTART:20160129T163000Z
DTEND:20160129T180000Z
UID:TALK63250@talks.cam.ac.uk
CONTACT:Louise White
DESCRIPTION:Anhedonia\, the lack of pleasure\, has been shown to be a crit
 ical feature of a range of neuropsychiatric disorders including MDD. Yet\,
  it is currently measured primarily through subjective self-reports and as
  such has been difficult to submit to rigorous scientific analysis. New in
 sights from affective neuroscience hold considerable promise in improving 
 our understanding of anhedonia and for providing useful objective behavior
 al measures to complement traditional self-report measures\, potentially l
 eading to better diagnoses and novel treatments. Reviewing the state-of-th
 e-art of hedonia research and specifically the established mechanisms of w
 anting\, liking\, and learning\, we propose to conceptualize anhedonia as 
 impairments in some or all of these processes\; thereby departing from the
  longstanding view of anhedonia as solely reduced subjective experience of
  pleasure. We discuss how deficits in each of the reward components can le
 ad to different expressions\, or subtypes\, of anhedonia affording novel w
 ays of measurement. Specifically\, we review evidence suggesting that pati
 ents suffering from depression and schizophrenia show impairments in wanti
 ng and learning\, while some aspects of conscious liking seem surprisingly
  intact. We show how advances in whole-brain computational modelling can h
 elp stratify the heterogeneity of anhedonia across neuropsychiatric disord
 ers\, depending on which parts of the pleasure networks are most affected.
  This in turn has implications for diagnosis and treatment of anhedonia.\n
 \nShort bio:\nProfessor Morten L Kringelbach is the director of Hedonia Re
 search Group based at the universities of Oxford and Aarhus. His research 
 seeks to understand the pleasure systems (hedonia) in the human brain in h
 ealth and disease to increase well-being (eudaimonia). This pursuit requir
 es a multidisciplinary and transnational approach using tools from neurops
 ychiatry\, neuroimaging\, neurosurgery\, psychology\, philosophy\, anthrop
 ology and computer science. Professor Kringelbach is a Fellow of the Assoc
 iation for Psychological Science\, on the editorial board of Social Neuros
 cience and a member of the advisory board of Scientific American. He has p
 ublished fourteen books\, and over 250 scientific papers\, chapters and ot
 her articles. 
LOCATION:Ground Floor Lecture Theatre\, Department of Psychology
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