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SUMMARY:How the sins of your grandparents affect your health - Dr Erica Wa
 tson PDN\, Cambridge
DTSTART:20160121T160000Z
DTEND:20160121T170000Z
UID:TALK63372@talks.cam.ac.uk
CONTACT:Sarah Harrison
DESCRIPTION:Environmental exposure to stressors\, such as dietary deficien
 cy\, might have an impact on  epigenetic regulation of gene expression. Th
 is may increase your risk for disease over the course of your lifetime. Re
 cent studies show that this disease risk might be epigenetically inherited
  between generations via the germline\, affecting the health and developme
 nt of your grandprogeny and great grandprogeny. Our research uses a mouse 
 model of abnormal folate metabolism to understand the epigenetic mechanism
  behind  transgenerational inheritance of developmental phenotypes. Not on
 ly does this work shed light onto the role of folate metabolism during dev
 elopment\, which has eluded researchers for decades\, but it also give us 
 new insight into disease prevention methods\, the effects of which may not
  be observed for multiple generations
LOCATION:Hodgkin Huxley Seminar Room\, Physiology Building\, Downing Site
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