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SUMMARY:Tissue-like materials from communicating droplet networks - Profes
 sor Hagan Bayley\, University of Oxford
DTSTART:20160412T150000Z
DTEND:20160412T160000Z
UID:TALK63378@talks.cam.ac.uk
CONTACT:Alice Wood
DESCRIPTION:Synthetic biology is being used to build devices through both 
 top-down and bottom-up approaches. For example\, genome engineering has be
 en used to reprogram cells\, and DNA origami has been used to produce a va
 riety of nanodevices. While progress has been made on the bottom-up assemb
 ly of minimal cells\, synthetic tissues have so far received limited atten
 tion. \n\nWe have assembled networks of aqueous droplets joined by lipid b
 ilayers. The droplets in the networks can communicate with each other and 
 with the environment through engineered protein pores. To mimic tissues\, 
 droplet networks should be endowed with various properties including the a
 bility to store and use energy\, to move and change shape\, to detect sign
 als\, to carry out computations and take up and release molecules. \n\nTo 
 a modest degree\, these goals have been achieved and like tissues the netw
 orks can exhibit emergent properties. Further\, designed networks of many 
 thousands of droplets have been fabricated by 3D printing. We aim to inter
 face droplet networks with living tissues and control them with electrical
  or optical signals
LOCATION:Pfizer LT
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