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SUMMARY:The heritability and prediction of complex human traits - Dr Alber
 t Tenesa\, University of Edinburgh
DTSTART:20160204T140000Z
DTEND:20160204T150000Z
UID:TALK63985@talks.cam.ac.uk
CONTACT:Narinder Bansal
DESCRIPTION:The main focus of my lab is to understand the contribution of 
 genetic and environmental factors to the aetiology of complex disease and 
 medically related complex traits\, as well as\, to investigate how to best
  use these factors in the prediction of disease.\n \nIn the first part of 
 the talk\, I will present evidence that a part of the missing heritability
  can be explained by an overestimation of heritability due to shared famil
 ial environmental effects.\nIn the second part\, I will show that the use 
 of a powerful statistical approach and large samples sizes provide conside
 rable improvements of prediction accuracy of complex traits compared to ty
 pically used polygenic risk scores.
LOCATION:Thomas Strangeways Room\, Strangeways Research Laboratory
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