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SUMMARY:The Tangled World of Reactive Oxygen Species: the Search for the B
 ad Actors in Ambient Particles - Prof Suzanne Paulson\, UCLA
DTSTART:20160222T141500Z
DTEND:20160222T151500Z
UID:TALK64479@talks.cam.ac.uk
CONTACT:Peter Gallimore
DESCRIPTION:Reactive oxygen species (ROS) produced by inhaled ambient part
 icles may contribute to a variety of adverse health outcomes\, and play a 
 role in aerosol aging. ROS includes the hydroxyl radical\, hydrogen peroxi
 de and superoxide\, and other species\; some ROS assays may also be sensit
 ive to organic hydroperoxides. Measuring ROS is growing in popularity by a
 tmospheric chemists\, driven largely by the question of what components of
  particles or types of particles are more likely to cause disease. There a
 re a large number of ROS assays in use with no clear leader in terms of th
 e most predictive of disease outcomes. To make mattes more complicated\, R
 OS production is normally monitored in aqueous extraction solutions\, the 
 composition of which has a substantial effect on the outcome.  Further\, t
 here is the matter of timescale\; some ROS are presumably present in the p
 articles initially while others are generated by the particles over timesc
 ales of hours or more. The talk will present results of recent field campa
 igns in California as well as laboratory results with a focus on the most 
 active transition metals\, iron\, copper and manganese\, and the strong ro
 le of biomass burning\, where present\, and their relative activity in thr
 ee different ROS assays. These will be discussed in the context of the mat
 rix of ROS assay approaches.
LOCATION:Unilever Lecture Theatre\, Department of Chemistry
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