BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Brain State Control by Closed-Loop Environmental Feedback - Taro T
 oyoizumi\, RIKEN Brain Science Institute
DTSTART:20160321T110000Z
DTEND:20160321T120000Z
UID:TALK65239@talks.cam.ac.uk
CONTACT:Guillaume Hennequin
DESCRIPTION:Brain state regulates sensory processing and motor control for
  adaptive behavior. Internal mechanisms of brain state control are well st
 udied\, but the role of external modulation from the environment is not we
 ll understood. Here\, we examined the role of closed-loop environmental (C
 LE) feedback\, in comparison to open-loop sensory input\, on brain state a
 nd behavior in diverse vertebrate systems. In fictively swimming zebrafish
 \, CLE feedback for optomotor stability controlled brain state by reducing
  coherent neuronal activity. The role of CLE feedback in brain state was a
 lso shown in a model of rodent active whisking\, where brief interruptions
  in this feedback enhanced signal-to-noise ratio for detecting touch. Fina
 lly\, in monkey visual fixation\, artificial CLE feedback suppressed stimu
 lus-specific neuronal activity and improved behavioral performance. Our fi
 ndings show that the environment mediates continuous closed-loop feedback 
 that controls neuronal gain\, explaining brain state phenomena\, and that 
 neuronal processing is an emergent property of brain-environment interacti
 ons.
LOCATION:Cambridge University Engineering Department\, CBL\, BE-438 (http:
 //learning.eng.cam.ac.uk/Public/Directions)
END:VEVENT
END:VCALENDAR