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SUMMARY:&quot\;A non-stationary Bayesian model for across-site heterogenei
 ty in molecular phylogenetics&quot\; - Dr Sarah Heaps\, University of Newc
 astle
DTSTART:20160705T133000Z
DTEND:20160705T143000Z
UID:TALK65257@talks.cam.ac.uk
CONTACT:Alison Quenault
DESCRIPTION:Standard phylogenetic models of molecular sequence evolution a
 ssume that the evolutionary process is homogeneous across sites and statio
 nary over time. However\, these assumptions are known to be biologically u
 ntenable and the implied sequence properties are discordant with those of 
 many real data sets. We describe a non-stationary model which allows heter
 ogeneity in the patterns of substitution across sites through a site-speci
 fic quadratic transformation of a baseline rate matrix. This generalises t
 he commonly applied approach of allowing site-specific scaling of an under
 lying rate matrix.
LOCATION:Large  Seminar Room\, 1st Floor\, Institute of Public Health\, Un
 iversity Forvie Site\, Robinson Way\, Cambridge
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