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SUMMARY: Enhancing nanopore sensing with DNA nanotechnology - Ulrich F. Ke
 yser\, Cavendish Laboratory\, University of Cambridge	
DTSTART:20160420T093000Z
DTEND:20160420T103000Z
UID:TALK65735@talks.cam.ac.uk
CONTACT:Jerome Charmet
DESCRIPTION:Nanopores are on the brink of fundamentally changing DNA seque
 ncing. At the same time\, DNA origami provides unprecedented freedom in mo
 lecular design. Here\, I suggest why a combination of solid-state nanopore
 s and DNA nanotechnology will lead to exciting new experiments. I will int
 roduce a novel way to detect and identify single proteins by using DNA car
 riers. With DNA nanotechnology we buitd carriers that allow for digitally 
 encoding information and thus unambiguous protein identification and conce
 ntration measurements down to nanomolar levels. This opens the pathway to 
 massively multiplexed nanopore sensing of proteins [1] and other small bio
 molecules. \n\n\n[1] N. A. W. Bell and U. F. Keyser.\nDigitally encoded DN
 A nanostructures for multiplexed\, single-molecule protein sensing with na
 nopores.\nNature Nanotechnology\, published online\, 2016. 
LOCATION:Department of Chemistry\, Cambridge\, Unilever lecture theatre
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