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SUMMARY:The comparative landscape of duplications in Heliconius melpomene 
 and Heliconius cydno  - Ana Pessoa Pinharanda - Department of Zoology
DTSTART:20160422T153000Z
DTEND:20160422T160000Z
UID:TALK65905@talks.cam.ac.uk
CONTACT:Kira Tipping
DESCRIPTION:Gene duplications can facilitate adaptation and may lead to in
 ter-population divergence\, causing reproductive isolation. We used whole-
 genome re-sequencing data from 34 butterflies to detect duplications in tw
 o Heliconius species\, H. cydno and H. melpomene. Taking advantage of thre
 e distinctive signals of duplication in short-read sequencing data\, we id
 entified 744 duplicated loci in H. cydno and H. melpomene. Duplications ov
 erlap genes significantly less than random in H. melpomene\, consistent wi
 th the action of background selection against duplicates in functional reg
 ions of the genome. Duplicate loci that are highly differentiated between 
 H. melpomene and H. cydno are widely distributed across the genome. Nine d
 uplications may be under selection\, including two duplications in close p
 roximity with known wing colour pattern loci that differ between the two s
 pecies\, several gustatory receptors and an odorant binding protein. These
  candidates merit further investigation for a potential role in host plant
  and mate recognition differences between the species.
LOCATION:Tea Room\, Department of Zoology
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