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SUMMARY:Multi-scale modelling of stochastic gene expression - Vahid Shahre
 zaei (Imperial College London)
DTSTART:20160606T140000Z
DTEND:20160606T150000Z
UID:TALK66358@talks.cam.ac.uk
CONTACT:INI IT
DESCRIPTION:Genetically identical cells exhibit variability in gene expres
 sion due   to inherent stochasticity in biochemical reactions. In this sem
 inar\, I   describe a multi-scale approach that includes modelling cell gr
 owth\,   division and proliferation in addition to stochastic gene express
 ion   inside individual cells. I then discuss three short stories that use
 s   this approach. Firstly\, how cell growth rate regulates gene expressio
 n    noise\, secondly\, how does expression of fitness inducing gene is   
  shaped by proliferation and finally how to infer parameters of gene expre
 ssion from single cell data.
LOCATION:Seminar Room 2\, Newton Institute
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