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SUMMARY:Woofing it down – lessons on the neurobiology of appetite from m
 an’s best friend - Dr Eleanor Raffan\, Postdoctoral Research Fellow\, Ca
 nine Obesity Group\, WT-MRC Institute of Metabolic Science\, Cambridge
DTSTART:20161102T160000Z
DTEND:20161102T170000Z
UID:TALK66417@talks.cam.ac.uk
CONTACT:Fiona Roby
DESCRIPTION:Obesity is a big problem in dogs and humans.  We have exploite
 d the unusual genetic architecture within dog breeds to discover a mutatio
 n in the gene POMC in Labrador dogs which predisposes them to obesity and 
 high food motivation.  The mutation prevents production of a neuroactive p
 eptide which is important in humans but has previously been difficult to s
 tudy because it is not produced by rodents.  Ongoing studies are examining
  the role of POMC in energy homeostasis and investigating further genetic 
 causes for breed-related differences in obesity susceptibility.
LOCATION:Lecture Theatre 2\, Department of Veterinary Medicine
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