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SUMMARY:Path integral-based Bayesian inference of bond energy and mobility
  - Tom Chou (University of California\, Los Angeles)
DTSTART:20160622T080000Z
DTEND:20160622T084500Z
UID:TALK66541@talks.cam.ac.uk
CONTACT:INI IT
DESCRIPTION:<span><br>Co-authors: Josh Chang (NIH)\, Pak-Wing Fok (Univ. o
 f Delaware)<br><br> A Bayesian interpretation is given for regularization 
 terms for<br> parameter functions in inverse problems. Fluctuations about 
 the<br> extremal solution depend on the regularization terms - which encod
 e<br> prior knowledge - provide quantification of uncertainty. After<br> r
 eviewing a general path-integral framework\, we set up a number of<br> app
 lications that arise in biophysics. The inference of bond energies<br> and
  bond coordinate mobilities from dynamic force spectroscopy<br> experiment
 s are worked out in detail.<br><br> Related Links <a href="http://faculty.
 biomath.ucla.edu/tchou/" target="_blank" rel="nofollow">http://faculty.bio
 math.ucla.edu/tchou/</a></span>
LOCATION:Seminar Room 1\, Newton Institute
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