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SUMMARY:Traditional and Genetic Risk Factors for Coronary Heart Disease: F
 irst versus Subsequent Events - Dr Riyaz Patel\, Senior Clinical Research 
 Fellow at Institute of Cardiovascular Science\, UCL
DTSTART:20160615T130000Z
DTEND:20160615T140000Z
UID:TALK66549@talks.cam.ac.uk
CONTACT:Dr Peter Willeit
DESCRIPTION:Patients with coronary heart disease (CHD) have high long-term
  morbidity and mortality\, yet our ability to identify or intervene in tho
 se at greatest risk is limited. Risk factors for subsequent CHD events hav
 e been understudied with an assumption that they are likely to precisely o
 verlap with those for first CHD events. Our group is testing the hypothesi
 s that differences in risk factor associations in these two settings could
  exist\, which in turn may inform (1) better risk prediction (2) mechanist
 ic insights and (3) new drug development for secondary prevention. We are 
 examining\, at scale\, the association of selected genetic and phenotypic 
 CHD risk factors with risk of subsequent events by utilizing previously un
 available resources\, harnessing large scale data through linked electroni
 c health records of 10 million UK patients\, a new global consortium of CH
 D cohorts with DNA and the UK Biobank. 
LOCATION:Thomas and Dorothy Strangeways Room\, Strangeways Research Labora
 tory\, Wort’s Causeway\, Cambridge\, CB1 8RN
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