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SUMMARY:The role of cell competition in tumour growth - Saskia Suijkerbuij
 k (Pidini lab\, Gurdon Institute/ Kops lab\, Utrecht)
DTSTART:20161116T173000Z
DTEND:20161116T193000Z
UID:TALK66912@talks.cam.ac.uk
CONTACT:Clara Sidor
DESCRIPTION:In tissues\, growth and survival of cells depends on relative 
 fitness levels. The\nstrongest cells are selected while the less fit cells
  are eliminated through a\nprocess known as cell competition. We have rece
 ntly shown that in the adult\nDrosophila posterior midgut growing tumors u
 se cell competition to kill surrounding\ncells and cause host tissue attri
 tion. Inhibition of cell competition prevents\nadenoma growth\, indicating
  that it is an essential driver of tumor growth in this\ntissue. This talk
  will highlight our findings in the fly model and our current\nadvances in
  the development of mammalian models for cell competition.
LOCATION:Gurdon Institute Tea Room
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