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SUMMARY:Biomolecular condensates and their implications for neurodegenerat
 ive disease - Tony Hyman\, Max Planck Institute of Molecular Cell Biology 
 and Genetics\, Dresden
DTSTART:20171012T120000Z
DTEND:20171012T130000Z
UID:TALK67462@talks.cam.ac.uk
CONTACT:Kate Davenport
DESCRIPTION:Cells organize many of their biochemical reactions by formatio
 n and dissolution of non-membrane-bound compartments. Recent experiments s
 how that a common mechanism for such biochemical organization is phase sep
 aration of unstructured proteins to form liquid-like compartments.  These 
 liquid-like compartments can be described by principles elucidated from co
 ndensed-matter physics and are therefore termed biomolecular condensates. 
  I will discuss the relationship between the formation of liquid like comp
 artments\, and the onset of aggregated-protein pathology that is commonly 
 observed in neurodegenerative diseases.
LOCATION:CRUK CI Lecture Theatre
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