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SUMMARY:Validation &amp\; testing of novel therapeutic targets to treat os
 teosarcoma - Dr Branden Moriarity\, Department of Pediatrics\, University 
 of Minnesota
DTSTART:20171010T123000Z
DTEND:20171010T133000Z
UID:TALK67804@talks.cam.ac.uk
CONTACT:47497
DESCRIPTION:Dear All\, \n \nThe Cambridge Institute Scientists’ Society 
 (CISS) would like to invite you all to our biannual seminar series on 10 O
 ctober 2016 at 13:30 in the CRUK CI Lecture Theatre\n \nOur guest lecturer
  is: Assistant Prof. Branden Moriarity in the Department of Paediatrics\, 
 Division of Hematology/Oncology at the University of Minnesota. Branden is
  an expert in genome engineering with emphasis on animal models of rare pa
 ediatric cancers and immunotherapy. It will be a fantastic talk and we hop
 e to see you all there!!\n \nTalk title: \nValidation & testing of novel t
 herapeutic targets to treat osteosarcoma\n \nResearch summary/interests:\n
 Pediatric cancer genetics\, gene and immunotherapy\, genome engineering. D
 r. Moriarity’s laboratory is working on studying the genetics of pediatr
 ic cancer\, including sarcomas and brain tumors\, to identify novel therap
 eutic targets to better treat pediatric cancer patients. The Moriarity lab
  uses animal models and comparative genomics approaches to identify new ca
 ndidate cancer genes. Once identified\, candidate genes are functionally s
 tudied in human cancer and immortalized cell lines using cutting edge tech
 nologies\, such as targeted nucleases. The primary targeted nucleases used
  in the Moriarity lab are the CRISPR/Cas9 and Transcriptional Activator-Li
 ke Effector (TALEN) systems\, which are used to knockout genes\, induce ta
 rgeted sequence changes\, activate and/or repress endogenous gene expressi
 on.\n \nAll welcome to attend.         \n \nKind regards\, \nCISS committe
 e
LOCATION:Cancer Research UK Cambridge Institute\, Lecture Theatre
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