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SUMMARY:Mapping the molecular landscape of disease - Erin Oerton (Universi
 ty of Cambridge)
DTSTART:20161111T122000Z
DTEND:20161111T124000Z
UID:TALK68028@talks.cam.ac.uk
CONTACT:Lisa Masters
DESCRIPTION:Recent innovations in the fields of genomics and transcriptomi
 cs have provided new insight into disease biology at a molecular scale.  M
 uch of this data is shared in public repositories\, enabling large-scale c
 omparative analysis of disease at the molecular level.  Such analysis can 
 reveal shared mechanisms between diseases previously considered to be unre
 lated\, improving our understanding of disease biology and pathology.   Fu
 rther\, shared molecular pathways between diseases can suggest new opportu
 nities for drug repositioning (the use of known compounds in new indicatio
 ns)\, significantly reducing drug development time compared to de novo dru
 g design.  In this talk I will outline how different feature spaces of dis
 ease can be integrated to associate diseases and drugs at multiple molecul
 ar levels.
LOCATION:Unilever Lecture Theatre\,  Department of Chemistry
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