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SUMMARY:Developing tools to map the brain at synaptic resolution - Marta C
 osta (Dept. Genetics) and Philipp Schlegel (Dept. Zoology / L.M.B)
DTSTART:20161207T183000Z
DTEND:20161207T200000Z
UID:TALK68301@talks.cam.ac.uk
CONTACT:Mark Dunning
DESCRIPTION:The Drosophila mushroom body (MB) is a complex neuropil\, used
  as a model for associative memory storage and state-dependent behaviours.
  In an international effort\, we are generating a wiring diagram of the MB
  and MB-associated neurons at synaptic resolution using an electron micros
 copy volume of the entire fruit fly brain. In order to manage a project on
  this scale\, analytic tools have been developed to manage and analyse mas
 sive amounts of data. \n\nOne of these is NBLAST\, a neuron similarity alg
 orithm that compares the shape and position of two neurons\, and returns a
  similarity score. NBLAST is able to distinguish neuron types and identify
  new ones. NBLAST can also be used to organise large datasets of neurons i
 nto groups of similar ones\, making it easier to deal with big volumes of 
 data. \n\nWe will describe the MB project\, touching on technical challeng
 es\, the NBLAST algorithm\, and its available resources.
LOCATION:Postdoc Centre\, 16 Mill Lane
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