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SUMMARY:Computational Neuroscience Journal Club - Rodrigo Echeveste (CBL)
DTSTART:20161018T150000Z
DTEND:20161018T160000Z
UID:TALK68622@talks.cam.ac.uk
CONTACT:Daniel McNamee
DESCRIPTION:Rodrigo Echeveste will cover:\n\n* Diversity in neural firing 
 dynamics supports both rigid and learned hippocampal sequences\n* Andres G
 rosmark\, György Buzsáki\n* Science (March 2016)\n* "Link to paper":http
 ://science.sciencemag.org/content/351/6280/1440\n\nABSTRACT:\nCell assembl
 y sequences during learning are “replayed” during hippocampal ripples 
 and contribute to the consolidation of episodic memories. However\, neuron
 al sequences may also reflect preexisting dynamics. We report that sequenc
 es of place-cell firing in a novel environment are formed from a combinati
 on of the contributions of a rigid\, predominantly fast-firing subset of p
 yramidal neurons with low spatial specificity and limited change across sl
 eep-experience-sleep and a slow-firing plastic subset. Slow-firing cells\,
  rather than fast-firing cells\, gained high place specificity during expl
 oration\, elevated their association with ripples\, and showed increased b
 ursting and temporal coactivation during postexperience sleep. Thus\, slow
 - and fast-firing neurons\, although forming a continuous distribution\, h
 ave different coding and plastic properties.
LOCATION:Cambridge University Engineering Department\, CBL\, BE-438 (http:
 //learning.eng.cam.ac.uk/Public/Directions)
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