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SUMMARY:Skipping between Portals: neutron analysis of membrane protein bio
 genesis - Dr Nathan R. Zaccai -Cambridge Institute for Medical Research
DTSTART:20161104T174500Z
DTEND:20161104T191000Z
UID:TALK68884@talks.cam.ac.uk
CONTACT:Dr Armando  Maestro
DESCRIPTION:Contrast Variation Small Angle Neutron Scattering (SANS) has p
 rovided important insights into the biogenesis of membrane proteins in Gra
 m-negative bacteria. Their cell envelope consists of two membranes\, which
  differ with respect to their lipid composition\, but also in the structur
 e of their integral membrane proteins. Importantly\, the latter are synthe
 sised in the cytoplasm and therefore have to be transported to their corre
 ct membrane. SANS analysis of integral membrane translocons and soluble ch
 aperones involved in this process have clarified the molecular basis of bi
 ological function\, as well as revealed unexpected conserved mechanisms pr
 esent in eukaryotic organisms.\n
LOCATION:Wolfson College\, Gatsby Room
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