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SUMMARY:Gut microbiota affects skin wound healing of mice by activating im
 mune-endocrine-brain axis elements - Dr. Theofilos Poutahidis\, Aristotle 
 University of Thessaloniki\, Thessaloniki\, Greece
DTSTART:20170131T090000Z
DTEND:20170131T093000Z
UID:TALK69734@talks.cam.ac.uk
CONTACT:Ilana Spilka
DESCRIPTION:Using mice we have shown that edible Lactobacillus reuteri acc
 elerates skin wound healing. The wounds of animals consuming either live o
 r lysed probiotic bacteria healed in half the time required for matched co
 ntrol animals. Experiments involving genetically engineered mice and cell 
 transfer methodologies suggest that this phenomenon is mediated by regulat
 ory T cells and the hormone oxytocin\, which is consistently upregulated a
 fter the consumption of L. reuteri. This result showcases that the gut mic
 robiome and host animal interact via immune-endocrine-brain signaling netw
 orks. Exploiting this interaction opens a new window for preventing and th
 erapeutic strategies based on edible bacteria products.
LOCATION:Online
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