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SUMMARY:EU Life Lecture - “Rembrandt: Remodelling the brain in intellect
 ual disability”  - Dr. Mara del Mar Dierssen Sotos\; CRG-Centre for Geno
 mic Regulation\, Barcelona
DTSTART:20170523T120000Z
DTEND:20170523T130000Z
UID:TALK70262@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:The main research interest in my laboratory is to decipher bra
 in mechanisms sub serving learning and memory\, and how they are altered i
 n cognitive pathology. We aim at understanding how the neuronal architectu
 re and connectivity constrain the mesoscopic network activity and influenc
 es the flow and storage of information in neuronal circuits in cognitive-r
 elated disorders. We use behavioural\, molecular and structural techniques
  in genetically modified model organisms to interrogate basic principles o
 f intellectual disability. Also\, we obtain structural experimental data f
 rom cleared brains which constrain computational modelling and analysis to
 ols to explore the neuronal circuit topologies to understand the organizat
 ional principles of mammalian neuronal networks. Finally\, we are interest
 ed in applying all this knowledge to develop new therapeutic tools targeti
 ng neural plasticity which rewire molecular networks\, including epigenomi
 c state\, to recover impaired structural and functional features in cognit
 ive pathology.
LOCATION:Babraham - The Brian Heap Seminar Room
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