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SUMMARY:Melville Lecture 2: Rational Strategy for Chain-Growth Supramolecu
 lar Polymerization - Professor Takuzo Aida\, University of Tokyo 
DTSTART:20170209T160000Z
DTEND:20170209T170000Z
UID:TALK70764@talks.cam.ac.uk
CONTACT:Sharon Connor
DESCRIPTION:We have developed the first rational strategy for ‘chain-gro
 wth’ supramolecular polymerization composed of defined initiation and pr
 opagation steps\, featuring ‘metastable’ bowl-shaped monomers that are
  designed to polymerize at ambient temperatures only when mixed with tailo
 red initiators\, and succeeded in forming noncovalent polymers with a unif
 orm and desired chain length in a precise stereoselective manner.  Over th
 e last decade\, significant progress in supramolecular polymerization\, in
 itiated by Lehn and Meijer and their coworkers has had a substantial impac
 t on the design of functional soft materials.1\,2  However\, despite recen
 t advances for obtaining polymers with narrow PDI\, most studies are still
  based on a preconceived notion that supramolecular polymerization follows
  the step-growth mechanism\, which precludes control over chain-length\, s
 equence\, and stereochemical structure.  Here we report the realization of
  chain-growth polymerization by designing metastable monomers with a shape
 -promoted intramolecular hydrogen-bonding network.3  The monomers are conf
 ormationally restricted from spontaneous polymerization at ambient tempera
 tures\, but begin to polymerize with characteristics typical of a living m
 echanism upon mixing with tailored initiators.  The chain growth occurs st
 ereoselectively and therefore enables optical resolution of a racemic mono
 mer. \n \nReferences (1) J. -M. Lehn\, Macromol. Chem. Macromol. Symp. 199
 3\, 69\, 1.  (2) E. W. Meijer et al.\, Science 1997\, 278\, 1601.  (3) Kan
 g and Miyajima et al.\, Science 2015\, 347\, 646. \n 
LOCATION:Wolfson Lecture Theatre\,  Department of Chemistry
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