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SUMMARY:Athena SWAN - My Life in Science Seminar - &quot\;An alternative r
 oute to an independent research career&quot\; - Dr Susan Campbell\; Lectur
 er\, Biomedical Research Centre\, Sheffield Hallam University
DTSTART:20170421T120000Z
DTEND:20170421T130000Z
UID:TALK70878@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:Susan was awarded her BA (Mod) in Microbiology from Trinity Co
 llege Dublin\, Ireland. She continued her studies at Trinity College and c
 ompleted a PhD entitled ' The regulation of 3' end processing under the su
 pervision of Prof Ursula Bond. She continued with Prof Bond as a research 
 associate investigating the adaptation of yeast brewing stress to high wor
 t environments before moving initially to UMIST and then to The University
  of Manchester\, where she carried out postdoctoral research on the impact
  of environmental stress on translation initiation in yeast\, in the lab o
 f Dr Mark Ashe. In 2013 she took up the position of Senior lecturer at She
 ffield Hallam University\, her research focuses on how the localisation of
  proteins within cells impacts upon their function. It is becoming increas
 ingly evident that compartmentalisation of the cytoplasm of cells into dis
 crete regions\, enables efficient control of translation initiation. Under
 standing the regulation of this localisation is a key theme within her res
 earch. In particular\, she is interested in how the compartmentalisation o
 f translation initiation factors within a cell impact upon their function 
 and how this may be important in addressing the molecular mechanisms behin
 d diseases classically associated with translational deregulation. In part
 icular\, the neurodegenerative disease childhood ataxia with central nervo
 us system hypomyelination (CACH) or leukoencephalopathy with vanishing whi
 te matter (VWM) has been linked to mutations in the translation initiation
  complex eIF2B and the molecular mechanisms behind how these mutations may
  impact upon these complexes of eIF2B is a key question within her researc
 h.
LOCATION:Babraham - The Brian Heap Seminar Room
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