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SUMMARY:Beyond the battlefield – New Frontiers in Cancer Research - Jenn
 ifer Harris\, MRC Cancer Unit
DTSTART:20170223T131000Z
DTEND:20170223T140000Z
UID:TALK71194@talks.cam.ac.uk
CONTACT:KC Sivaramakrishnan
DESCRIPTION:For decades\, our approach to curing cancer has been to define
  the precise molecular changes undergone by tumour cells. With an applied 
 understanding of environmental and genetic factors and the availability of
  high-throughput sequencing technology and well-designed animal models\, o
 ur knowledge within the field of tumour biology has grown in leaps and bou
 nds. Therapeutically\, this has translated to the design of some successfu
 l novel agents that target the tumour cell at a molecular level. However f
 or a large percentage of cancer patients\, these therapies are inadequate.
  Research has hence more recently started exploring cancer beyond the conv
 entional tumour cell focus\, acknowledging the many other factors at play 
 within the tumour microenvironment (TME). It is being increasingly recogni
 sed that these factors play a key role in immune editing\, metastasis and 
 drug resistance. The specific question my PhD asks\, is how a subset of va
 sculature within the TME\, plays an active role in tumour progression and 
 the establishment of metastatic niches in distal sites.\n\nBio: I attended
  the University of Plymouth from 2009 where in studied BSc in Biomedical S
 ciences (Hons) with placement. During my 18 months away from studies\, I w
 orked at the University of Oxford and the Human Genetics Foundation in Tur
 in\, Italy and developed a research interest in immune modulation and the 
 tumour microenvironment. Upon graduating in 2013\, I moved to the Universi
 ty of Cambridge to start a research MPhil with Dr. Jacqui Shields at the M
 RC Cancer Unit\, looking at the role of stroma in the modulating anti-tumo
 ur immunity. Thankfully I was able to continue in the lab\, staying on for
  my PhD\, for which I am now in my 3 rd year. In addition to pipetting fra
 ntically in the lab\, I have founded the Addenbrooke’s Graduate Forum\, 
 which helps bring employers to the life sciences graduate community\, and 
 engage in a range of science policy and communication events. I also love 
 running\, hiking\, music and was a member of Darwin’s DarBar committee f
 or 3yrs.
LOCATION:The Richard King Room\, Darwin College
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