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SUMMARY:‘Non-coding RNA - new roles for old players’ - Professor Ander
 s Lund\, Biotech Research and Innovation Centre\, University of Copenhagen
DTSTART:20170307T113000Z
DTEND:20170307T123000Z
UID:TALK71247@talks.cam.ac.uk
CONTACT:Mala Jayasundera
DESCRIPTION:Speaker Background:\n\nThe aim of the laboratory is to unveil 
 fundamental biological mechanisms and understand how these become perturbe
 d during diseases\, most prominently cancer\, with the ambition that our f
 indings may contribute to the development of clinical tools. We focus main
 ly on various classes of non-coding RNAs\, such as microRNAs\, snoRNAs\, t
 RNAs and lncRNAs. In addition\, we study RNA binding proteins and RNA modi
 fications. Special focus areas include the regulation of central tumor sup
 pressor pathways and autophagy.\n\n\nRecent papers:\n\n·       Damas\, N.
 D. et al. (2016). SNHG5 promotes colorectal cancer cell survival by counte
 racting STAU1-mediated mRNA destabilization. Nature Communications\, doi:1
 0.1038/ncomms13875.\n\n·       Montes\, M.\, et al. (2015). The lncRNA MI
 R31HG regulates p16INK4a expression to modulate senescence. Nature Communi
 cations. DOI: 10.1038/ncomms7967.\n\n·       Fog\, C.K.\, et al. (2015). 
 Loss of PRDM11 promotes B cell lymphomagenesis. Blood. 125: 1272-1281.\n\n
 ·       Frankel\, L.B.\, et al.  (2014). A non-conserved miRNA regulates 
 lysosomal function and impacts human lysosomal storage disorders. Nature C
 ommunications. DOI: 10.1038/ncomms6840.\n\n·       Gingold\, H.\, Tehler\
 , D\, et al. (2014). A dual program for translation regulation in cellular
  proliferation and differentiation. Cell 158:1281-1292.\n\n\nHomepage: htt
 p://www.bric.ku.dk/Research/Lund_Group/\n\n
LOCATION:Sackler Lecture Theatre (Level 7)\, Cambridge Institute for Medic
 al Research
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