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SUMMARY:&quot\;Circular Inference in schizophrenia...and all of us&quot\; 
 - Sophie Deneve\, Laboratoire de Neurosciences Cognitives\, Paris
DTSTART:20170515T153000Z
DTEND:20170515T170000Z
UID:TALK71579@talks.cam.ac.uk
CONTACT:Lyn Dakin
DESCRIPTION:Schizophrenia is a complex and heterogeneous mental disorder\,
  whose neuropathology started being understood only recently. However\, si
 nce the time of Kraepelin and Bleuler\, much information has been accumula
 ted on behavioural abnormalities usually encountered in schizophrenia pati
 ents. Despite recent progress\, how the latter is caused by the former sti
 ll remains debated. Here we argue that Circular Inference\, a computationa
 l framework proposed as a potential explanation for various schizophrenia 
 symptoms\, could help closing this gap. Based on Marr’s three levels of 
 analysis\, we discuss how impairments in local and more global neural circ
 uits could generate aberrant beliefs\, with far-ranging consequences from 
 probabilistic decision making to high-level visual perception in condition
 s of ambiguity. Interestingly\, the Circular Inference Framework appears c
 ompatible with a variety of pathophysiological theories of schizophrenia w
 hile being able to simulate behavioral symptoms.\n
LOCATION:The Hodgkin Huxley Seminar Room\, Department of Physiology Develo
 pment and Neuroscience
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