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SUMMARY:Coordination of spindle positioning and cell cycle progression in 
 yeast - Dr. Gislene Pereira\, German Cancer Research Center\, Heidelberg 
DTSTART:20170504T130000Z
DTEND:20170504T140000Z
UID:TALK71584@talks.cam.ac.uk
CONTACT:Caroline Newnham
DESCRIPTION:The positioning of the mitotic spindle along the mother-daught
 er cell polarity axis is critical for the outcome of cell division in asym
 metrically dividing budding yeast cells. A surveillance mechanism\, known 
 as the spindle position checkpoint (SPOC)\, senses defects in spindle orie
 ntation thereby inhibiting mitotic exit and cytokinesis. I will discuss ou
 r currently understanding of SPOC activation and how temporal and compartm
 ent-specific regulatory networks determine mitotic exit in this system.
LOCATION:Biffen Lecture Theatre\, Department of Genetics\, Downing Site
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