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SUMMARY:Mass Spectrometry Imaging in Drug Discovery: The Challenges and Op
 portunities for Molecular Imaging from Single Cells\, Preclinical Models a
 nd Through to Intraoperatively - Richard Goodwin (AstraZeneca)
DTSTART:20170419T134000Z
DTEND:20170419T141500Z
UID:TALK72006@talks.cam.ac.uk
CONTACT:INI IT
DESCRIPTION:Mass spectrometry imaging (MSI) is impacting on multiple stage
 s of drug discovery and supports established histopathology imaging. MSI o
 ffers the ability to simultaneously map the distribution of endogenous (me
 tabolites\, lipids and peptides) and exogenous compounds (drugs and their 
 metabolites) directly from the surface of tissue section. This can offer n
 ew routes into understanding drug efficacy and safety. The suite of MSI te
 chnologies that will be described are also capable of allowing translation
  into the clinic through analysis of patient biopsies and surgically colle
 cted tissues. Presented will be an overview of MSI in a drug discovery env
 ironment\, showcasing the current state of the art MSI technology platform
 s. We will also discuss the challenges that remain in the data and image a
 nalysis for this emerging molecular imaging modality.   <br><br><br><br>
LOCATION:Seminar Room 1\, Newton Institute
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