BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Epigenomics: When high-throughput sequencing met epigenetics - Mel
 anie Eckersley-Maslin and Christel Krueger (Babraham Institute)
DTSTART:20170607T173000Z
DTEND:20170607T190000Z
UID:TALK72550@talks.cam.ac.uk
CONTACT:Postdoc Masterclass
DESCRIPTION:In the last decade biological research has undergone a revolut
 ion brought about by high throughput sequencing technology. Epigenetic res
 earch aims to understand the dynamic regulation of gene expression: how ce
 ll fate decisions are made and maintained throughout life\, and how abbera
 nt regulation contributes to disease. Historically\, mechanisms have been 
 investigated at an individual gene level. Through epigenomics\, we can now
  study epigenetic events across millions of genes simultaneously enabling 
 us to establish global patterns and interdependencies.\n\nIn this Mastercl
 ass\, we will present an overview of what is epigenomics and the emerging 
 new technologies used to study it. We will introduce the different aspects
  of epigenetics from DNA methylation\, histone modification to nuclear org
 anisation\, and explore the different tools used to probe these layers of 
 information at a global scale. Excitingly\, these tools are also being ada
 pted to use on single cells allowing unprecedented insights into cell-to- 
 cell variability and heterogeneity. We will discuss these techniques in th
 e context of stem cell and developmental biology\, where the epigenome is 
 dynamic and critical for shaping cell identity.
LOCATION:Postdoc Centre\, 16 Mill Lane
END:VEVENT
END:VCALENDAR