BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Salamander regeneration: regulation and evolution - Professor Andr
 as Simon\, Karolinska Institute\, Stockholm
DTSTART:20170615T100000Z
DTEND:20170615T110000Z
UID:TALK73008@talks.cam.ac.uk
CONTACT:Birgitta Olofsson
DESCRIPTION:The ability to regenerate lost body structures is present in d
 iverse animal species ranging from simple organisms\, such as the hydra to
  complex vertebrates\, such as salamanders. We aim to understand how anima
 ls with outstanding regenerative capabilities sense what and how much is m
 issing in relation to the normal homeostatic state\, and how they translat
 e that information to the appropriate regenerative responses. We primarily
  study an aquatic salamander\, the newt\, which possesses exceptional rege
 nerative capacities among adult vertebrates.\n\nIn particular\, we focus o
 n how progenitor cells are created and characterize their developmental po
 tential during regeneration. We are currently generating comprehensive gen
 etic resources such as transcriptome\, genome databases\, and in vivo geno
 me editing tools for newts. We will use these genomic resources for gainin
 g deeper insights into salamander regeneration at the molecular level and 
 for cross-species comparisons with mammals in clinically relevant lesion/r
 egeneration settings. Our research might reveal fundamental aspects of cel
 l fate determination that could contribute to the design of novel regenera
 tive strategies.
LOCATION:Department of Zoology\, Main Lecture Theatre
END:VEVENT
END:VCALENDAR