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SUMMARY:The emergence of pluripotency and germline specification in non-ro
 dent mammals - Professor Ramiro Alberio (University of Nottingham)
DTSTART:20170615T150000Z
DTEND:20170615T160000Z
UID:TALK73067@talks.cam.ac.uk
CONTACT:Maria Schacker
DESCRIPTION:Pluripotent epiblast cells of early mammalian embryos give ris
 e to all the lineages that make up a fetus. How these cells emerge and wha
 t gene networks determine their identity has been a topic of much discussi
 on over recent years\, mainly due to differences reported between humans a
 nd mice. Indeed\, human and mouse embryos differ substantially during the 
 period when the epiblast develops\, and this seems to impact how embryonic
  lineages are determined.\nWe use pig embryos as a model for non-rodents s
 pecies\, because of the shared embryology with humans. I will present data
  showing conserved features of pluripotency and germline origin between hu
 mans and pigs and highlight important advantages of using the pig embryo a
 s a model for non-rodent mammalian development to complement studies on hu
 man embryos\n
LOCATION:Hodgkin Huxley Seminar Room\, Physiology Building\, Downing Site
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