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SUMMARY:Pulse and Surge Generation by the GnRH Neuronal Network for Fertil
 ity - Professor Allan Herbision
DTSTART:20170704T150000Z
DTEND:20170704T160000Z
UID:TALK73195@talks.cam.ac.uk
CONTACT:William Colledge
DESCRIPTION:The gonadotropin-releasing hormone (GnRH) neurons have an unus
 ual neuronal phenotype in that they migrate from the nose into the brain d
 uring embryogenesis to ultimately control reproductive hormone secretion a
 nd fertility in all vertebrates. The GnRH neurons embed themselves into a 
 neuronal network that enables them to generate two different types of epis
 odic activity that drive “pulse" and “surge" patterns of hormone secre
 tion. Studies in genetically manipulated mice using viral tract-tracing\, 
 electrophysiology\, and a range of in vivo optogenetic and chemogenetic ap
 proaches are beginning to shed light on the key neuronal circuitries respo
 nsible for driving these different modes of episodic activity.
LOCATION:Hodgkin-Huxley Lecture Room\, Department of Physiology Developmen
 t and Neuroscience
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