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SUMMARY:Motility induced elongation of the vertebrate embryo - Ido Regev (
 Ben-Gurion University)
DTSTART:20170919T111000Z
DTEND:20170919T113000Z
UID:TALK80121@talks.cam.ac.uk
CONTACT:INI IT
DESCRIPTION:<span>   <span>While   the genotype provides an instruction se
 t for morphogenesis\, how those   instructions are converted to shape invo
 lves physical patterning as cells   change their relative number\, size\, 
 shape and position in space and time\, in   conjunction with chemical grad
 ients that they are driven by and in turn   drive. We study one of the sim
 plest geometrical motifs in morphogenesis\, the   elongation of the verteb
 rate embryo\, and show how spatially modulated   expression of a specific 
 signaling molecule Fgf8 leads to variations in   motility and density. Our
  experiments and theory show how just a few cellular   parameters that con
 trol activity and mechanics allow us to quantify the   characteristic scal
 e over which elongation occurs and also determines a   typical velocity of
  the elongation of the body.<br>     <br>     This work was done in collab
 oration with Karine Guevorkian\, Olivier   Pourqui&#39\;e and L. Mahadevan
 .</span></span>
LOCATION:Seminar Room 1\, Newton Institute
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