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SUMMARY:‘Worms\, fish\, cats and dogs’-Insights in to the pathogenesis
  of polycystic kidney diseases - Dr Richard Sandford\, Wellcome Trust Seni
 or Fellow in Clinical Research\, University Reader in Renal Genetics\, Dep
 artment of Medical Genetics\, Cambridge Institute of Medical Research\, Ad
 denbrooke's Hospital
DTSTART:20080206T163000Z
DTEND:20080206T173000Z
UID:TALK8053@talks.cam.ac.uk
CONTACT:Penny Watson
DESCRIPTION:Abstract\nIn man polycystic kidney diseases are a major cause 
 of ill health in adults and children. Genes for many of these diseases\, i
 ncluding autosomal dominant polycystic kidney disease (OMIM 173900) and au
 tosomal recessive polycystic kidney disease (OMIM 263200) have recently be
 en identified. Functional characterisation in several different model syst
 ems has shown that many cystic kidney disease genes regulate the structure
  and function of the primary cilium. This structure appears to act as an e
 nvironmental sensor and the signaling pathways and functions that it regul
 ates are currently being defined. Ciliopathies now form the basis of a new
  field of molecular\, developmental and clinical research. \n
LOCATION:Lecture Theatre 1\, Department of Veterinary Medicine
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