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SUMMARY:Genomics for precision oncology: How hard can it be? - Professor C
 ristin Print\, University of Auckland
DTSTART:20170929T110000Z
DTEND:20170929T120000Z
UID:TALK81371@talks.cam.ac.uk
CONTACT:Sue Griffin
DESCRIPTION:Genomics and bioinformatics are transforming our biological kn
 owledge of cancer. These technologies promise great things for cancer pati
 ents and their families. However\, first efforts to use these technologies
  in the clinic by simply matching mutations to drugs have not been success
 ful in all tumour types. Perhaps a more nuanced use of cancer genomic info
 rmation is required for patients with genetically complex tumours? \n\nThi
 s talk will describe our experiences using genomics to analyse tissue and 
 blood from patients with genetically complex or highly aneuploid tumours\,
  including neuroendocrine tumours\, Merkel cell carcinomas and melanomas. 
 Based on our experience\, we suggest that for genetically complex tumours 
 including tumours driven by aneuploidy\, integrated histopathological anal
 ysis alongside analysis of copy number and RNA expression\, as well as DNA
  sequencing\, is required to identify genetic drivers and therapeutic opti
 ons.
LOCATION:Lecture Theatre\, Department of Pathology\, Tennis Court Road
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