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SUMMARY:Cell morphogenesis across scales\, from molecular processes to cel
 l surface mechanics - Prof. Ewa Paluch\, MRC LMCB\, University College Lon
 don and  Physiology\, Development and Neuroscience\, University of Cambrid
 ge.
DTSTART:20180511T150000Z
DTEND:20180511T160000Z
UID:TALK87151@talks.cam.ac.uk
CONTACT:Lorenzo Di Michele
DESCRIPTION:A precise control of cell morphology is key for cell physiolog
 y\, and cell shape deregulation is at the heart of many pathological disor
 ders\, including cancer. Cell morphology is intrinsically controlled by me
 chanical forces acting on the cell surface\, to understand shape it is thu
 s essential to investigate the regulation of cellular mechanics.\n\nIn ani
 mal cells\, shape is primarily determined by the cellular cortex\, a thin 
 cytoskeletal network underlying the plasma membrane. We investigate how th
 e mechanical properties of the cell surface arise from the microscopic org
 anisation of the cortex\, and how changes in these properties drive cell d
 eformation. Using a combination of cell biology experiments\, quantitative
  imaging and physical modelling\, we aim to understand the control of cell
  shape across scales.\n
LOCATION:Small Lecture Theatre\, Cavendish Laboratory
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