BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Functional Genomics to Study Cancer - David Sabatini\, Whitehead I
 nstitute
DTSTART:20180628T120000Z
DTEND:20180628T130000Z
UID:TALK87991@talks.cam.ac.uk
CONTACT:Kate Davenport
DESCRIPTION:We are using genome-scale CRISPR-Cas9 genetic screens in a lar
 ge number of human cancer cell lines to study cancer. With this approach w
 e are defining oncogenic drivers\, synthetic lethal interactions\, and gen
 es that modulate the response to drug therapies. I will discuss the big pi
 cture lessons we have learned as well as the challenges we have encountere
 d. I will also present efforts to develop tissue culture media that better
  mimics the metabolic composition of human plasma and our efforts to under
 stand how the metabolic milieu affects the genetic dependencies of cancer 
 cells.\n\n
LOCATION:CRUK CI Lecture Theatre
END:VEVENT
END:VCALENDAR