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SUMMARY:Non-invasive electrophysiological recordings of human hippocampus 
 - Sofie Meyer\, UCL
DTSTART:20171106T123000Z
DTEND:20171106T133000Z
UID:TALK93799@talks.cam.ac.uk
CONTACT:Johan Carlin
DESCRIPTION:A lot of interesting behaviour of the hippocampus occurs on a 
 sub-second scale. Measuring this activity with magnetoencephalography (MEG
 ) remains challenging due to the hippocampus’ depth as well as the spati
 al uncertainty introduced during data acquisition and co-registration. In 
 this talk\, I will describe how the depth can be accounted for by anatomic
 al modelling\, and the spatial uncertainty minimized by using head-casts. 
 I will discuss recent results from an experiment combining these two metho
 ds with a spatial memory task known to give rise to hippocampal theta osci
 llations. I will demonstrate that this enables temporally resolved\, non-i
 nvasive\, in vivo recordings of human hippocampal activity using MEG. In a
 ddition\, I will discuss how these measurements accord with predictions fr
 om invasive rodent and human measurements. Finally\, I will show data reco
 rded with new non-cryogenic MEG sensors which can be placed directly on th
 e scalp\, and discuss the potential for these sensors to replace conventio
 nal cryogenic MEG.
LOCATION:Lecture Theatre\, MRC Cognition and Brain Sciences Unit\, 15 Chau
 cer Road\, Cambridge
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