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SUMMARY:Computational Neuroscience Journal Club - Alberto Bernacchia (CBL)
DTSTART:20171031T160000Z
DTEND:20171031T170000Z
UID:TALK94591@talks.cam.ac.uk
CONTACT:Rodrigo Echeveste
DESCRIPTION:Alberto Bernacchia will cover:\n\n• Ring attractor dynamics 
 in the Drosophila central brain\n\n• Sung Soo Kim\, Hervé Rouault\, Sha
 ul Druckmann\, Vivek Jayaraman\n\n• Science (May 2017)\n\n• http://sci
 ence.sciencemag.org/content/early/2017/05/03/science.aal4835\n\nAbstract: 
 Ring attractors are a class of recurrent networks hypothesized to underlie
  the representation of heading direction. Such network structures\, schema
 tized as a ring of neurons whose connectivity depends on their heading pre
 ferences\, can sustain a bump-like activity pattern whose location can be 
 updated by continuous shifts along either turn direction. We recently repo
 rted that a population of fly neurons represents the animal’s heading vi
 a bump-like activity dynamics. We combined two-photon calcium imaging in h
 ead-fixed flying flies with optogenetics to overwrite the existing populat
 ion representation with an artificial one\, which was then maintained by t
 he circuit with naturalistic dynamics. A network with local excitation and
  global inhibition enforces this unique and persistent heading representat
 ion. Ring attractor networks have long been invoked in theoretical work\; 
 our study provides physiological evidence of their existence and functiona
 l architecture.
LOCATION:Cambridge University Engineering Department\, CBL\, BE4-38 (http:
 //learning.eng.cam.ac.uk/Public/Directions)
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