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SUMMARY:3D normal coordinate systems for the cortex: applications in the d
 eafened cortices in babies\, adults and cats - Tilak Ratnanather (Johns Ho
 pkins University)
DTSTART:20171117T113000Z
DTEND:20171117T121500Z
UID:TALK95206@talks.cam.ac.uk
CONTACT:INI IT
DESCRIPTION:We describe a surface-based diffeomorphic algorithm to generat
 e 3D coordinate grids in the cortical ribbon. In the grid\, normal coordin
 ate lines from the grey/white (inner) surface to the grey/csf (outer) surf
 ace are constrained to be normal at the surfaces. Specifically\, the corti
 cal ribbon is described by two triangulated surfaces with open boundaries.
  Conceptually\, the inner surface sits on top of the white matter structur
 e and the outer on top of the gray matter. It is assumed that the cortical
  ribbon consists of cortical columns which are orthogonal to the white mat
 ter surface. This might be viewed as a consequence of the development of t
 he columns in the embryo. It is also assumed that the columns are orthogon
 al to the outer surface. So if we construct a vector field such that the i
 nner surface evolves diffeomorphically towards the outer one\, the distanc
 e of the resultant trajectories will be a measure of thickness. Applicatio
 ns will be described for the deafened auditory cortices in babies\, adults
  and cats. The approach offers potential for quantitative functional and h
 istological analysis of cortical activity and anatomy.  <br><span><br>(Joi
 nt work with Laurent Younes\, Sylvain Arguill&egrave\;re\, Kwame Kutten\, 
 Andrej Kral\, Peter Hubka and Michael Miller).&nbsp\;</span>
LOCATION:Seminar Room 1\, Newton Institute
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