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SUMMARY:Mechanics of a Volvox Embryo Turning Itself Inside Out - Pierre Ha
 as (University of Cambridge)
DTSTART:20171123T150000Z
DTEND:20171123T163000Z
UID:TALK95677@talks.cam.ac.uk
CONTACT:INI IT
DESCRIPTION:<span>The spherical embryos of the green alga Volvox turn them
 selves inside out through a programme of cell shape changes at the close o
 f their development. This inversion shares features such as invagination w
 ith events of cell sheet folding in animals\, and has therefore become a s
 imple model system for morphogenesis. Through the combination of three-dim
 ensional time-lapse visualisations of inversion and a theoretical model in
  which cell shape changes appear as variations of the intrinsic stretches 
 and curvatures of an elastic shell\, we identify the mechanical ingredient
 s necessary for inversion. We go on to quantify the variability of inversi
 on\, and use it to analyse the interplay of mechanics\, geometry\, and reg
 ulation during inversion. These analyses begin to reveal evolutionary aspe
 cts of developmental complexity in the Volvocalean algae.<br> Joint work w
 ith: Stephanie H&ouml\;hn\, Aurelia R. Honerkamp-Smith\, Julius B. Kirkega
 ard\, and Raymond E. Goldstein</span><br><br><br><br>
LOCATION:Seminar Room 2\, Newton Institute
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