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Cellular recycling: role of autophagy in aging and disease

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If you have a question about this talk, please contact Bobbie Claxton .

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The cytosolic recycling process of autophagy plays an important role in many age-related diseases and has been directly linked to aging, including in the nematode C. elegans where autophagy appears beneficially induced in many conserved longevity models. As a critical process to ensure cellular homeostasis, autophagy is regulated at multiple levels, yet it remains a challenge in the field to understand how the regulation of autophagy is integrated at the cellular and molecular level to ensure health- and lifespan benefits. I will here discuss our progress on understanding the different molecular mechanisms employed by cells and organisms to regulate autophagy in response to stressors such as aging and disease.

This talk is part of the Babraham Seminar series.

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Hicks & Mead Rooms, University Centre, Granta Place Cavendish Laboratory, Pippard Lecture Theatre & TEAMS Room 101, Hardy Building

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