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Dr Yanlan Mao, MRC Laboratory for Molecular Cell Biology, University College London
Thursday 14 October 2021, 13:30-14:30
Coping with Mechanical Stress: Tissue dynamics in development and repair
- đ¤ Speaker: Dr Yanlan Mao, MRC Laboratory for Molecular Cell Biology, University College London
- đ Date & Time: Thursday 14 October 2021, 13:30 - 14:30
- đ Venue: Zoom meeting
Abstract
During growth and development, tissue dynamics, such as tissue folding, cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maintain their shape after development. In this talk, we will discuss how differential growth rates can generate precise folds in tissues. We will also discuss how tissues respond to mechanical perturbations, such as stretching or wounding, by altering their actomyosin contractile structures, to change tissue dynamics, and thus preserve tissue shape and patterning. We combine genetics, biophysics and computational modelling to study these processes.
Series This talk is part of the Genetics Seminar series.
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