Exploring host-tumour metabolic interactions using Drosophila
- đ¤ Speaker: Dr Susumu Hirabayashi, MRC London Institute of Medical Sciences, Imperial College London
- đ Date & Time: Thursday 03 March 2022, 14:00 - 15:00
- đ Venue: Zoom meeting
Abstract
Cancer is increasingly viewed as a systemic disease associated with a range of host metabolic changes including obesity, insulin resistance, and cachexia/muscle wasting syndrome, each of which alters the host metabolic and nutritional environment. Cancer cells actively acquire nutrients from the extracellular space to support their growth, but how cancer cells sense and respond to changes in systemic nutrient availability remains incompletely understood. We leverage the fruit fly Drosophila melanogaster as a model system to explore host-tumour metabolic and nutritional interactions. In this seminar, I present how our Drosophila studies have started reveal mechanisms by which tumours sense and exploit extracellular nutrients in the context of both obesity and systemic muscle wasting. I also demonstrate how tumours with different genetic alterations respond differently to obesity.
Series This talk is part of the Genetics Seminar series.
Included in Lists
- All Talks (aka the CURE list)
- Bioinformatics and other interests
- Biology
- Centre for Health Leadership and Enterprise
- CPB Maria
- DevBio
- Genetics Seminar
- Genetics Seminar Series
- Graduate-Seminars
- ji247's list
- Life Sciences
- Life Sciences
- ME Seminar
- my_list
- ndk22's list
- Neurons, Fake News, DNA and your iPhone: The Mathematics of Information
- other talks
- PMRFPS's
- Zoom meeting
Note: Ex-directory lists are not shown.
![[Talks.cam]](/static/images/talkslogosmall.gif)

Dr Susumu Hirabayashi, MRC London Institute of Medical Sciences, Imperial College London
Thursday 03 March 2022, 14:00-15:00