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Josef Priller, University of Edinburgh & Technical University of Munich
Monday 09 May 2022, 16:00-17:00
Diversity of brain macrophages
- đ¤ Speaker: Josef Priller, University of Edinburgh & Technical University of Munich
- đ Date & Time: Monday 09 May 2022, 16:00 - 17:00
- đ Venue: https://zoom.us/j/93385021933?pwd=cnNabGRvL0lJUk9qKzFNNGpydTdCQT09 Meeting ID: 933 8502 1933 Passcode: bmBXz8QB2j
Abstract
The central nervous system (CNS) hosts a variety of tissue macrophages, including parenchymal microglia, as well as border-associated macrophages such as meningeal and perivascular macrophages. Recent studies using transgenic animals, transcriptomic and proteomic technologies have enhanced our understanding of the ontogeny and diversity of CNS macrophages. In this presentation, I will show that microglia and meningeal macrophages share a common prenatal progenitor, whereas perivascular macrophages originate only after birth in an integrin-dependent manner. The establishment of perivascular macrophages requires the presence of arterial vascular smooth muscle cells.
Series This talk is part of the Microglia webinar series series.
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